Patients enrolled underwent a baseline 12-lead ECG. PRECISION found in 2016 that celecoxib does not confer excess cardiovascular risk and is associated with fewer cardiovascular adverse events compared with both naproxen and ibuprofen in patients with rheumatoid arthritis or osteoarthritis. This post hoc analysis included 22,607 (94%) of the randomized, double-blind, multicenter PRECISION trial’s 24,081 patients. “Our analysis makes a strong case for recognizing any type of delayed LV conduction among well-recognized cardiovascular risk factors, and thus changing how we think about overall cardiovascular health.” New subclassification scheme for intraventricular conduction delay “We have long established that delayed left ventricular conduction in the form of left bundle branch block confers markedly increased risk for cardiovascular and overall mortality in patients,” says the study’s corresponding and senior author, Daniel Cantillon, MD, of Cleveland Clinic’s Section of Electrophysiology and Pacing. We do not endorse non-Cleveland Clinic products or services Policy Advertising on our site helps support our mission. Cleveland Clinic is a non-profit academic medical center.
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